A clinical trial is an important part of the process involved in researching treatments and medicines for a medical condition. It helps determine if a proposed solution works or is useless. It may not work as expected, or work in some patients but not in others. If the problems are serious or affect a large percentage of participants, the solution may be discarded. The solution can go back to the lab for improvement if it is promising. MPN clinical trials are used to find treatments for MPNs.

A clinical trial can involve only a few or thousands of participants. It depends on the stage of the trial and the number of patients needed to certify the claim of successful treatment. In some cases, the side effects may not be serious and the solution may get approval with some conditions. It may be possible to identify the risk groups and they can be excluded from receiving that treatment.